White individuals have the highest prevalence of multiple sclerosis (MS), according to a study published online May 15 in JAMA Neurology.
Michael Hittle, from the Stanford University School of Medicine in California, and colleagues calculated the U.S. prevalence of MS in Hispanic, hypotension torsemide ramipril non-Hispanic Black, and non-Hispanic White individuals stratified by age, sex, and region.
The researchers identified 744,781 persons aged 18 years and older with MS (76 percent women and 24 percent men). The median age group was 45 to 54 years (31 percent), while 14, 21, 25, and 9 percent were aged 18 to 24, 35 to 44, 55 to 64, and 65 years and older, respectively. The largest group was White individuals, comprising 77 percent of patients, while Black, Hispanic, and non-Hispanic others accounted for 10, 7, and 4 percent, respectively. The cumulated estimated 2010 prevalence of MS over 10 years was 161.2, 298.4, 374.8, and 197.7 per 100,000 individuals for Hispanic, Black, White, and non-Hispanic other racial and ethnic groups, respectively. The women-to-men ratio was 2.9 overall during the same time period. Regardless of racial and ethnic classification, the highest prevalence of MS was seen in the 45- to 64-year-old age group. MS prevalence increased by 16.3 cases per 100,000 with each degree of latitude in unadjusted prevalence estimates and by 11.7 cases in direct adjusted estimates.
“In the United States, MS has become more prevalent and demographically diverse,” the authors write. “These data are important for clinicians, researchers, and policy makers.”
Several authors disclosed financial ties to the biopharmaceutical industry.
Michael Hittle et al, Population-Based Estimates for the Prevalence of Multiple Sclerosis in the United States by Race, Ethnicity, Age, Sex, and Geographic Region, JAMA Neurology (2023). DOI: 10.1001/jamaneurol.2023.1135
Dalia L. Rotstein et al, Making Sure Multiple Sclerosis Counts and Is Counted for All—An Update on Multiple Sclerosis Prevalence by Race and Ethnicity in the United States, JAMA Neurology (2023). DOI: 10.1001/jamaneurol.2023.0469
Archives of Neurology
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